Gut Hormone Screen


Investigation of patients with gastrointestinal symptoms suggestive of a neuroendocrine tumour (NET) or screening for multiple endocrine neoplasia type I.


  • Gastrin
  • Glucagon
  • Pancreatic polypeptide
  • Vasoactive intestinal polypeptide
  • Somatostatin
  • Chromogranin A and B

Sampling requirements

Patient preparation

  • Complete overnight fast.
  • H2 receptor antagonists including ranitidine, cimetidine, famotidine, nizatidine should be stopped for 72 hours prior to testing.
  • PPIs including omeprazole, lansoprazole and pantoprazole should be stopped for 2 weeks prior.

Specimen requirements

  • 2 x EDTA sample sent to the laboratory on ice within 15 minutes of collection. 


Provided on report by referral laboratory.


Other Comments:

Analysed at SAS Endocrine Laboratory, Clinical Biochemistry, 8th Floor, Charing Cross Hospital, Imperial College NHS Healthcare Trust, Fulham Palace Road, London, W6 8RF


About This Test

Department: Biochemistry (referred)


  • 2 x EDTA (purple top)

Dedicated samples required

Turnaround Time:

6 - 8 weeks